What is PNH?
PNH is an acquired mutation that causes some or all of your body’s red blood cells (RBCs) to be destroyed by a process called hemolysis.2-4 PNH is a complex disease with signs and symptoms that are nonspecific, unpredictable, and often similar to those of other diseases. In addition, PNH presents uniquely in each person. If you have PNH, some or all of your RBCs may be missing an important protective protein. Without this protein, RBCs are prone to destruction by a part of your body’s defense system called complement.
