What is Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL)?
Acute lymphoblastic leukemia (ALL) is a fast-growing malignant disorder resulting from a proliferation of white blood cells that fail to mature and accumulate in the bone marrow, destroying and replacing cells that produce normal blood cells. Prognosis declines with increasing age and is most unfavorable when the Philadelphia chromosome (Ph) is present.