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What is PDE-5 and what is its relationship to ED?

April 26, 2017Ed pde-5 relationship

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What is PDE-5 and what is its relationship to ED?

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Phosphodiesterase-5 or PDE-5 is an enzyme which converts cGMP (a key biochemical component of the erection process) from its active state to its inactive state. By inhibiting the function of PDE-5, the concentration of cGMP will increase helping the smooth muscles in the penis relax and widen, allowing more blood to enter. As a result, erections are more easily achieved.