What is partial blocking exactly?
Partial blocking occurs when Salicylate in numbers LESS than available kidney receptors arrives in the kidney at the SAME time that guaifenesin does. As these receptors attract salicylate like a magnet, Guai can’t bind to them. They are OCCUPIED. IF some receptors are still free then guai has a partial effect by binding to the limited open receptors. This comes down to quantity. IF there are 2000 receptors in a kidney and 1000 salicylate molecules arrive then 1000 will be available for guai to bind to. Hence partial blocking. Another instance of partial blocking can occur when salicylates are in the kidney for a brief time. They occupy all receptors for a while. If one is taking a time released medication, some of the guai during a 12 hour period it is active – will be flushed out. This is a more IFFY situation as we have no idea how long a salicylate molecule can remain bound to a kidney receptor. Back To Top How can I be sure I’m not blocking (Blocking Test Instructions) Relevant onl
