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What is PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections?

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What is PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections?

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The children that fit the PANDAS criteria must be diagnosed with OCD and/or a tic disorder, have a prepubertal symptom onset, an episodic clinical course tied to group A b-hemolytic streptococcal infections (GABHS/strep. throat infections), and the presence of other neurological abnormalities. The typical PANDAS child will contract a strep. infection and shortly thereafter develop sudden onset OCD and/or tics. These children may also develop separation anxiety, sleep problems, an increase in urinary frequency, a sudden onset of bed-wetting, hyperactivity/inability to pay attention, difficulties with fine motor control, and a marked increase in irritability. Eventually, these symptoms will remit until the child has another strep. infection, and then the cycle will begin again. More information about PANDAS is available at the following website:http://intramural.nimh.nih.gov/research/pdn/gen_info.

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The children that fit the PANDAS criteria must be diagnosed with OCD and/or a tic disorder, have a prepubertal symptom onset, an episodic clinical course tied to group A b-hemolytic streptococcal infections (GABHS/strep. throat infections), and the presence of other neurological abnormalities. The typical PANDAS child will contract a strep. infection and shortly thereafter develop sudden onset OCD and/or tics. These children may also develop separation anxiety, sleep problems, an increase in urinary frequency, a sudden onset of bed-wetting, hyperactivity/inability to pay attention, difficulties with fine motor control, and a marked increase in irritability. Eventually, these symptoms will remit until the child has another strep. infection, and then the cycle will begin again.

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