What is Ovarian Hyperstimulation Syndrome (OHSS)?
is a condition in which many follicles are produced and cause accumulation of fluid in the abdomen and sometimes in the chest. The abdominal fluid causes bloating. The fluid in the chest causes breathlessness. This condition is usually temporary. However women with poly cystic ovaries have an increased sensitivity to FSH and are more susceptible to severe hyperstimulation. Sometimes, admission to hospital is required and drainage of the accumulated fluid from the abdomen and occasionally from the chest may be done. Treatment with concentrated albumin infusion is effective in correcting this condition. The preferred approach is to avoid this complication of IVF. If there are numerous growing follicles, one way is to cancel the cycle by omitting the HCG trigger. In this approach as there is almost no risk of hyperstimulation. A fresh cycle can be started with a lower dose of FSH. Another way is to proceed with the HCG trigger (5,000 units), harvest all the follicles and freeze store the
Ans 29: When we stimulate ovaries with genadotrophin it may get overstimulated sometimes producing more than many follicles. This may lead to very high level of estrodial & patient may land with OHSS. If this complication is mild to moderate, can be treated. But sever OHSS may lead to hospitalization. Pregnency if occurs will add fuel to problem.
This is a condition in which many follicles are produced and cause accumulation of fluid in the abdomen and sometimes in the chest. The abdominal fluid causes bloating. The fluid in the chest causes breathlessness. This condition is usually temporary. However women with poly cystic ovaries have an increased sensitivity to FSH and are more susceptible to severe hyperstimulation. Sometimes, admission to hospital is required and drainage of the accumulated fluid from the abdomen and occasionally from the chest may be done. Treatment with concentrated albumin infusion is effective in correcting this condition. The preferred approach is to avoid this complication of IVF. If there are numerous growing follicles, one way is to cancel the cycle by omitting the HCG trigger. In this approach as there is almost no risk of hyperstimulation. A fresh cycle can be started with a lower dose of FSH.Another way is to proceed with the HCG trigger, harvest all the follicles and freeze store the embryos fo