What is osteoarthritis and what is S-Adenosylmethionine (SAMe)?
Osteoarthritis (OA) is a disease of the joints, such as your knee or hip. When the joint loses cartilage, the bone grows to try to repair the damage. Instead of making things better, however, the bone grows abnormally and makes things worse. For example, the bone can become misshapen and make the joint painful and unstable. This can affect your physical function or ability to use your knee. S-Adenosylmethionine is popular dietary supplement available over the counter in drug stores or health food stores. It is also a naturally occurring chemical that is produced in the body. SAMe is not found in foods, so it must be taken as a supplement. Best estimate of what happens to people with osteoarthritis who take S-Adenosylmethionine (SAMe) Pain – People with S-Adenosylmethionine and people with placebo are equally likely to respond to treatment (difference of 0%). This could be the result of chance. – People who took S-Adenosylmethionine had an improvement in their pain of about 2 on a scale
