What is nonsyndromic deafness, autosomal recessive?
Nonsyndromic deafness is hearing loss that is not associated with other signs and symptoms. In contrast, syndromic deafness involves hearing loss that occurs with abnormalities in other parts of the body. Nonsyndromic deafness is often genetic and can be described by its pattern of inheritance. An autosomal recessive inheritance pattern means that two copies of an altered gene are present in each cell. Autosomal recessive deafness is designated DFNB. Each type is numbered in the order in which it was described. For example, DFNB1, DFNB2, and DFNB3 are particular forms of autosomal recessive deafness. Nonsyndromic deafness, autosomal recessive is a subtype of nonsyndromic deafness. Most forms of autosomal recessive deafness are characterised by hearing loss from birth. The level of hearing loss varies within and among families. Autosomal recessive deafness is typically caused by changes to structures in the inner ear. The inner ear consists of three parts: a snail-shaped structure calle
Nonsyndromic deafness is hearing loss that is not associated with other signs and symptoms. Nonsyndromic deafness is often genetic and can be described by its pattern of inheritance. An autosomal recessive inheritance pattern means that two copies of the gene must be altered for a person to be affected. Nonsyndromic deafness, autosomal recessive is a subtype of nonsyndromic deafness. Most forms of autosomal recessive deafness are characterized by stable, severe to profound hearing loss from birth. The hearing loss is sensorineural, which means that it is caused by changes in the inner ear. The level of hearing loss varies within and among families.
