What is Nonoxynol-9, and is it safe to use?
Nonoxynol-9 (N-9) is a chemical that is commonly used in spermicides. N-9 has been proven to be ineffective in stopping HIV and other sexually transmitted infections (STIs) from being passed on from person to person. In fact, using N-9 frequently (more than once a day) can also increase vaginal irritation, which may actually increase the risk of becoming infected with HIV or other STIs from infected partners. For these reasons, N-9 should not be used to prevent HIV. This means you should not use condoms that have been treated with N-9.