What is non-surgical microbiologically modulated antimicrobial periodontal therapy?
Initially developed in the 1970s by legendary dental researcher Dr. Paul H. Keyes at the National Institutes of Health (NIH), and sometimes referred to as the “Keyes Technique”, it is a system for treating periodontal disease as a dental plaque-mediated bacterial infection, with specific disease-associated dental plaque microorganisms targeted for elimination or suppression on a sustained basis to extremely low levels compatible with clinical periodontal stability and health. In this approach as it has evolved to the present day, locally-applied antimicrobial agents during dental office appointments and in daily patient home care procedures, as well as short-term systemic antibiotic regimens on occasion, are used to supplement the benefits of conventional non-surgical periodontal therapy. In addition to standard clinical measurements and radiographic observations, the patient’s periodontal therapy is also regulated and adjusted using phase-contrast microscopic and/or microbial culture