WHAT IS NEUROFIBROMATOSIS TYPE II?
Neurofibromatosis Type II, (NF2) also known as Multiple Inherited Schwannomas, Meningiomas and Ependymomas (MISME) is a genetically inherited disease. It is distinguishable from NF Type 1, also known as von Recklinghausen’s disease. The primary manifestation of NF2 is a development of non-malignant (benign) brain tumors in the region of the cranial nerves, frequently bilaterally. The eighth cranial nerve is the auditory-vestibular nerve which transmits sensory information from the inner ear to the brain and is commonly affected. NF II is caused by mutations of the “Merlin” gene, which appears to influences the form and movement of cells.
