What is necrosis in cancer disease?
NECROSIS is the name given to accidental death of cells and living tissue. Necrosis is less orderly than apoptosis, which is part of programmed cell death. In contrast apoptosis, cleanup of cell debris by phagocytes of the immune system is generally more difficult, as the disorderly death generally does not send cell signals which tell nearby phagocytes to engulf the dying cell. This lack of signalling makes it harder for the immune system to locate and recycle dead cells which have died through necrosis than if the cell had undergone apoptosis. The release of intracellular content after cellular membrane damage is the cause of inflammation in necrosis.- Tumor necrosis factor is a protein produced by several of the body’s cell types, such as white blood cells, red blood cells, and other cells that line the blood vessels. It promotes the destruction of some types of cancer cells. In the 1970s, researchers took sarcoma cells in culture and exposed them to a protein produced by white bloo
