What is Myelodysplastic/Myeloproliferative disease (MDS/MPD)?
The myelodysplastic syndromes (MDS) are a diverse collection of blood disorders characterized by an ineffective production of blood cells. The myeloproliferative diseases (MPDs) are a group of diseases of the bone marrow in which excess cells are produced. Myelodysplastic/myeloproliferative overlap disorders (MDS/MPD) are malignant stem cell disorders that have both dysplastic and proliferative features at the time of initial presentation, resulting in increased numbers of immature cells in the bone marrow and a decrease in mature, functional cells in the blood.
