What is MPD (Myeloproliferative Disease)?
“Myelo” is the Greek word for marrow “Proliferative” means growing or reproducing “Disease” is the improper function of a body organ. MPD is literally “Marrow Proliferative Disease” or improper function of the bone marrow organ. Bone marrow is the body’s blood-forming (hematopoietic) organ. It contains blood-forming cells called “pluripotent hematopoietic precursor or stem cells” (PHPC) that have two important functions. (1) self-renewal to maintain a pool of stem cells for future proliferation or growth. (2) ability to mature into adult blood cells that will leave the marrow and enter the circulation. These precursor cells produce several types of blood cells: red blood cells (RBC), several varieties of white blood cells (WBC), and platelets. Each PHPC is a stem cell that can reproduce itself (clone) as well as produce a number of daughter cells (blasts).
“Myelo” is the Greek word for marrow “Proliferative” means growing or reproducing “Disease” is the improper function of a body organ. MPD is literally “Marrow Proliferative Disease” or improper function of the bone marrow organ. Bone marrow is the body’s blood-forming (hematopoeitic) organ. It contains blood-forming cells called “hematopoeitic precursor or stem cells” that have two important functions: 1. self-renewal to maintain a pool of stem cells for future proliferation or growth. 2. ability to mature into adult blood cells that will leave the marrow and enter the circulation.. These precursor cells produce several types of blood cells; red blood cells (RBC), some varieties of white blood cells (WBC) and plalelets. Because of this versatility, they are called “pluripotential hematopoeitic precursor cells (“PHPC”). Each PHPC is a stem cell that can reproduce itself (clone) as well as produce a number of daugher cells (blasts). Normal bone marrow is composed of a family of hematopoe
MPD is literally “Marrow Proliferative Disease” or improper function of the bone marrow organ. Bone Marrow is the soft tissue located in the cavities of bones and is responsible for Blood cell and platelet production. When Bone Marrow start producing more than normal blood cell, then this condition is called MPD (Myeloproliferative Disease) Who Can Get Polycythemia Vera ? Polycythemia Vera is basically a disease of older age but can be found in young people but its very rare. More men are affected by PV than women. Its frequency is also low. There are only about five cases per year for every one million people. It is more common in adults older than sixty years. It is more prevalent among Jews of Eastern European descent.
