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What is Model Standard Deviation?

April 26, 2017deviation model standard

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What is Model Standard Deviation?

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In DIA, a plot is generated of the number of spots against log[volume ratio] and this should show a normal distribution (red line in graph view, DeCyder™ DIA see Fig 2). As the samples are related, most of the spots will show no change (ratio = 1, log[volume ratio] = 0) so the peak should be centered on 0. The software locates this peak, fits it to a model histogram and then centers this at zero. The model standard deviation is the standard deviation of the model histogram (blue line in graph view, DeCyder DIA see Fig 2). This gives the user an idea of the variation associated with the largest peak of spot ratios. For further information please refer to the Ettan DIGE System User Manual.