What is meant by a soluble versus insoluble chemical substance?
In theory, use of the term solubility in the TLVs for metals refers to its solubility in biological fluids, especially in the lung. However, water solubility often is used as a surrogate for this. For more detailed information please see the TLV Documentation for the specific substance of interest and the “Q&A Column” in the December, 1995 issue of ACGIH Today!.