What is Leptin Resistance?
If everything is working properly, when the body has accumulated enough stored fat, adipocytes release leptin. The leptin crosses the blood brain, signaling you to stop eating sooner which stops the accumulation of fat. Leptin Resistance is a chronic inflammatory problem that can lead to slow, steady weight gain. When researchers began investigating the role of leptin in the body, they quickly ran into a paradox. While leptin is known to control hunger, researchers found that overweight people frequently have extremely elevated plasma leptin levels. As counterintuitive as this seems, researcher were able to determine that leptin resistance was responsible for this problem. Much in the same way type-2 diabetics become insulin resistant, people can become leptin resistant. Unlike diabetics, treatment isn’t as simple as injecting more leptin into the body. The problem is two-fold. First obesity and weight gain are associated with higher inflammation. The higher inflammation is associated
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