What is known about the safety of squalene in vaccines?
Twenty two million doses of Chiron’s influenza vaccine (FLUAD) have been administered safely since 1997. This vaccine contains about 10 mg of squalene per dose. No severe adverse effects have been associated with the vaccine. Some mild local reactogenicity has been observed. Clinical studies on squalene-containing vaccines have been done in infants and neonates without evidence of safety concerns.
