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What is known about the neurological mechanism of action for salvinorin A?

April 26, 2017Action known mechanism neurological salvinorin

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What is known about the neurological mechanism of action for salvinorin A?

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. Salvinorin A is a potent, highly selective kappa opioid receptor agonist. Experimental evidence indicates that the psychoactive effects of salvinorin A result from its activity at these receptors. Self-experiments performed by Daniel Siebert have demonstrated that the effects of salvinorin A are inhibited by pre-administration of the opioid receptor antagonist, naloxone.