What is known about the nausea reported in BYETTA clinical trials?
In clinical trials, nausea was mostly mild to moderate and it occurred most commonly upon initiation of therapy. Of BYETTA-treated patients, 3% withdrew due to nausea over the course of the entire 30-week clinical trials. Initiation of BYETTA at 5 mcg BID for at least a month followed by dose escalation to 10 mcg BID has been found to minimize the occurrence of nausea.