What is known about medium-term health effects of Jadelle use?
The best evidence of medium-term health effects comes from the five-year Norplant postmarketing surveillance. The surveillance compared some 8,000 Norplant users with about 8,000 users of either IUDs or sterilization in eight developing countries. The women were followed for five years, even if they discontinued use of the method, switched to another, or became pregnant. Norplant was not associated with any material risk of major morbidity compared with the two control groups. For greater detail, see the section on the postmarketing surveillance in this monograph.