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What is Interstitial Fluid (ISF) and how is it different from blood?

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What is Interstitial Fluid (ISF) and how is it different from blood?

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Interstitial fluid is the fluid in spaces between the cells in your body. Movement of nutrients, oxygen and glucose from the blood into the cells occurs across the blood vessel wall and interstitial fluid. Depending on how glucose is being consumed by surrounding cells and how rapidly the glucose is changing, there may be some differences between the glucose levels in capillary blood (which home blood glucose meters measure) and interstitial fluid. Typically, these differences are not significant enough to affect treatment decisions. These differences can be magnified during conditions of rapid changes in the blood glucose levels (for example, after eating, exercising or dosing insulin).

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