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What is happening in the brain to cause the problems associated with this disease?

April 26, 2017associated brain cause disease happening problems

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What is happening in the brain to cause the problems associated with this disease?

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The gene associated with the production of aspartoacylase does not work properly in Vincents brain, which leads to an accumulation of NAA (N-acetylaspartic acid). This acid cannot be broken down and creates a sponginess in his brain that leads to the degeneration of myelin (white matter).