What is frameshift correction?
• Frameshift correction takes a gene that appears to be fragmented, and constructs a “conceptual translation” by attempting to join the fragments using single insertions and deletions to remove the apparent frameshift errors. However, sometimes it makes mistakes. Fragmented genes are bad for subsystem analysis, so the FIG Philosophy is that it is better to risk a few “false positive” repairs than to accept a large number of frameshift errors. Hence, FS repair is the default for SEED inclusion.
