What is fluorescence in situ hybridization?
FISH is a technique that measures gene amplification and chromosomal abnormalities using fluorescently labeled DNA probes. The fluorescently labeled DNA matches certain regions of DNA and when the matching regions come in contact they bind with each other. Presence of the stuck probe marks the areas of interest. The amount and location of the of bound probe are then analyzed to identify genes that have been copied abnormally or altered in some major way.
