What is excluded from the new select agent regulation (42 CFR 73)?
• Select agents or toxins that are in their naturally occurring environment, provided that it has not been intentionally introduced, cultivated, collected, or otherwise extracted from its natural source. • Non-viable select agent organisms or nonfunctional toxins. • The vaccine strain of Junin virus (Candid #1). • The vaccine strain of Rift Valley fever virus (MP-12). • Venezuelan Equine encephalitis virus vaccine strain TC-83. • It is possible under the new rule to apply for exclusion for any attenuated agent or toxin using an appropriate form obtainable from CDC. Exclusions for specific strains may be granted if the attenuated strain is determined not to pose a significant public health or safety threat. Exclusions will be published in the notice section of the Federal Register and will be listed on the CDC website at http://www.cdc.gov/od/sap. • Exclusions for entities with specific quantities of toxins under the control of a principal investigator at a given time are also detailed
