What is EVDB and SpliceMiner?
SpliceMiner and EVDB are precursors of SpliceCenter and it’s splice variant database. The Genomics and Bioinformatics Group of NCI’s Laboratory of Molecular Pharmacology in collaboration with the Bioinformatics Department of George Mason University developed SpliceMiner and EVDB. EVDB is a relational database that contains a comprehensive, non-redundant collection of splice variant data derived from NCBI’s Evidence Viewer. SpliceMiner is a web-based tool for querying EVDB and is most often used for high-throughput identification of microarray probe target locations. SpliceCenter now uses a different technique for building its splice variant database (see here) but EVDB laid the groundwork for the structure and utility of the current splice variant database. SpliceMiner has been retrofit to use the new splice variant database and is still useful for identifying probe target locations for novel microarrays.