What is estrogens role in menopause?
Estrogen production from the ovary begins to decrease as a woman enters perimenopause. It is estimated that estrogen levels drop to 40-60% of pre-menopausal levels. Other tissues in the body, most notably the adrenals and fat tissue, have the ability to produce estrogens. This accounts for some of the variation in estrogen production post-menopausally. The decrease in estrogen has been associated with a number of menopausal and perimenopausal symptoms. These include a change in cervical mucus causing vaginal dryness, thinning of the vaginal walls and changes in the endometrial lining which plays a role in irregular bleeding cycles. Although a decrease in estrogen has been associated with hot flashes, the mechanism is not completely understood, as evidenced by many women who supplement with estrogen but still suffer from hot flashes.
Estrogen production in the ovaries decreases as a woman enters perimenopause. It is estimated that estrogen levels drop to about 50% of pre-menopausal levels. Other tissues in the body, most notably the adrenals and fat tissue, have the ability to produce estrogens. This accounts for some of the variation in estrogen production post-menopausally. The decrease in estrogen has been associated with a number of menopausal and perimenopausal symptoms. These include a change in cervical mucus causing vaginal dryness, thinning of the vaginal walls and changes in the endometrial lining which plays a role in irregular bleeding cycles. Although a decrease in estrogen has been associated with hot flashes, the mechanism is not completely understood, as evidenced by many women who supplement with estrogen but still suffer from hot flashes.
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