What is estradiol vaginal (systemic)?
Estradiol is a form of estrogen. Estrogen is a female sex hormone necessary for many processes in the body. Estradiol vaginal (systemic) is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Some estradiol products placed directly into the vagina are used for “local” treatment of vaginal menopause symptoms involving the secretions and surrounding tissues of the vagina. Other vaginal estradiol products are used for treating menopause symptoms affecting the vagina as well as other parts of the body (such as hot flashes). This type of vaginal estradiol has “systemic” effects, meaning that it can affect parts of the body other than where the medicine is placed or applied. The information in this leaflet is specific to estradiol vaginal products used for systemic treatment of symptoms. Estradiol vaginal (systemic) may also be used for other purposes not listed in this medication guide.
