What is Eosinophilia-myalgia syndrome?
• Eosinophilia-myalgia syndrome: A rare condition that occurs in some people who take the antidepressant L-tryptophan. • Eosinophilia-myalgia syndrome: A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSPINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al.