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What is degenerative disc disease [DDD]? How it causes back pain?

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What is degenerative disc disease [DDD]? How it causes back pain?

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10

Degenerative disc disease refers to the loss of hydration in the disc and weakening of the annulus (outer lining of the disc). Degenerative disc disease is very common age related change in human being and many times it remains as asymptomatic change, not always painful. But, in some individual degeneration of the disc causes severe discogenic low back pain mainly, due to the chemical mediators which invade the avascular disc from outside.

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