What is cross-resistance?
Antimicrobial resistance is a complex phenomenon caused by a large variety of genetic determinants. Different determinants can encode resistance to the same antimicrobial agent. More importantly, a single determinant can encode resistance to several different antimicrobial agents at the same time. This latter phenomenon called cross-resistance is very frequent for antimicrobial agents belonging to the same antimicrobial class and seems to be the rule rather than the exception.