What is Creatine used for?
Traditional/Ethnobotanical uses Creatine was discovered in 1832 by the French chemist Michel Chevreul as an organic constituent of meat. Muscle work was later associated with creatine in 1847 when it was observed that the flesh of wild foxes killed in the chase contained 10 times more creatine than those living in captivity. In 1911, creatine was reported to be involved in muscle metabolism; it was demonstrated that oxygen consumption could be stimulated by adding creatine to muscle mince. In the early 1930s, it was suggested that creatine phosphate might serve as the source of energy for muscle contraction when its large free energy of hydrolysis (12 kcal/mol) was identified. By 1939, oxygen consumption was shown to be coupled to creatine phosphate synthesis in muscle, which confirmed that oxidative phosphorylation was indeed a function of creatine. In the late 1960s, researchers began using needle biopsy techniques to study the breakdown and resynthesis of adenosine triphosphate (ATP
