What is bradykinin-mediated angioedema?
Much less common is angioedema due to a genetic defect or caused by treatment with certain cardiovascular medications. In these forms of angioedema, bradykinin, a protein produced by the body, plays a central role. Bradykinin increases the permeability of the blood vessels, allowing fluid to escape from the vessels and enter the surrounding tissue and leading to angioedema. The forms of bradykinin-mediated angioedema include both hereditary angioedema (HAE) and different forms of acquired angioedema (AAE).
