What is Best vitelliform macular dystrophy?
Best vitelliform macular dystrophy (Best disease) is a form of macular degeneration characterized by a loss of central vision. It is also known by the name vitelliform macular dystrophy. FAQ: What are the symptoms? A: Best disease affects the macula, the central part of the retina responsible for fine visual detail and color perception. The retina and its component photoreceptor cells are essential to vision as they convert light into electrical impulses and then transfer these impulses to the brain via the optic nerve. Although the age of onset for those with Best disease can vary, it is usually diagnosed during childhood or adolescence. In the initial stages, a bright yellow cyst (fluid-filled sac) forms under the retinal pigment epithelium (RPE) beneath the macula. Upon examination, the cyst looks like a sunny-side-up egg. Despite the presence of the cyst, visual acuity may remain normal or near normal (between 20/30 and 20/50) for many years. Peripheral (side) vision usually remain
