What is AVASTIN and how does it work?
AVASTIN (pronounced ah-va΄-stin) is a monoclonal antibody. AVASTIN is given in combination with chemotherapy. While chemotherapy attacks the tumour directly, AVASTIN attacks the blood vessels that surround the tumour. In order to grow and spread, tumours need a constant supply of oxygen and other nutrients. Tumours get this supply by creating their own network of blood vessels. This process is called angiogenesis (an΄-gee-o-jen΄-i-sis). AVASTIN works by blocking angiogenesis. By preventing the growth of new blood vessels, AVASTIN helps starve the tumour of oxygen and other nutrients. This makes it hard for the tumour to grow. AVASTIN is given intravenously (through a needle placed in a vein in the arm, hand, or through a central line). Health Canada has authorized AVASTIN with conditions, under the Notice of Compliance with Conditions (NOC/c) Policy. This authorization reflects the promising nature of the clinical evidence which must be verified and/or extended with further studies. Pr
