What is anti-angiogenesis treatment?
Anti-angiogenesis is a targeted therapy using drugs or other substances to prevent tumors from creating new blood vessels, thus, stopping the growth of the tumor. Researchers are currently studying both natural and synthetic anti-angiogenesis inhibitors, and although many of these drugs are still available only in clinical trials, the first anti-angiogenesis drug, bevacizumab (Avastin), was approved by the Food and Drug Administration in February, 2004, for use in the treatment of metastatic colon cancer. A Phase II clinical trial of cisplatin, pemetrexed and bevacizumab for untreated mesothelioma and a Phase II trial of bevacizumab and erlotinib for previously treated mesothelioma are ongoing, and trials of other anti-angiogenesis agents are being tested in mesothelioma as well.
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