What is an urticarial reaction?
Hives and itching Treatment: Benadryl Foreign plasma proteins in the blood component cause this reaction. A mild urticarial reaction, if not associated with any other symptoms, is generally innocuous. Once the hives have resolved, the transfusion may be resumed with physician approval. Antihistamines may be administered before the blood transfusion as premedication to prevent urticaria for patients with known allergic reactions to blood.