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What is an Integral Membrane Protein?

integral membrane protein
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What is an Integral Membrane Protein?

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An integral membrane protein, also known as an IMP, is one which spans the entire biological membrane of a cell. These proteins are attached permanently to the cell membrane, and their function typically relies on being present in the membrane. Both structurally and functionally, they are integral parts of the membranes of cells. Each integral membrane protein molecule has an intricate relationship with the membrane within which it is situated. Structurally, the IMP is usually placed such that protein strands are woven throughout the structure of the cell membrane. Sections of protein protrude through the cell wall inside or outside the cell, or in both directions. The protein molecule cannot function if it is not embedded within the membrane.

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