What is an example of a germ-cell mutation?
If a gene is altered in a germ cell, the mutation is termed a germinal mutation. Because germ cells give rise to gametes, some gamete s will carry the mutation and it will be passed on to the next generation when the individual successfully mates. Typically germinal mutations are not expressed in the individual containing the mutation.Egs. In aneuploidy a normally diploid individual ends up either with extra copies of homologous chromosomes or fewer than the normal diploid number. This happens when homologous chromosomes fail to segregate poperly during meiosis. This failure of homologous chromsomes to segregate is called non disjunction. There are a number of different types of aneuploidy the most common types are monosomy in which the diploid individual has only one member of a certain homologous chromosome. The other common type of aneuploidy is called trisomy because the individual has three copies of the chromosome. Aneuplody leads to a number of syndromes in humans. For example t
