What is an aldosterone assay?
Definition This test measures the levels of aldosterone, a hormone produced by the outer part (cortex) of the two adrenal glands, organs which sit one on top of each of the kidneys. Aldosterone regulates the amounts of sodium and potassium in the blood. This helps maintain water balance and blood volume, which, in turn, affects blood pressure. Purpose Aldosterone measurement is useful in detecting a condition called aldosteronism, which is caused by excess secretion of the hormone from the adrenal glands. There are two types of aldosteronism: primary and secondary. Primary aldosteronism is most commonly caused by an adrenal tumor, as in Conn’s syndrome. Idiopathic (of unknown cause) hyperaldosteronism is another type of primary aldosteronism. Secondary aldosteronism is more common and may occur with congestive heart failure, cirrhosis with fluid in the abdominal cavity (ascites), certain kidney diseases, excess potassium, sodium-depleted diet, and toxemia of pregnancy. To differentiate