What is Alport syndrome?
Alport syndrome, also known as “hereditary nephritis” is a rare inherited disorder that can affect not only the kidneys, but also hearing and vision. Named after the physician who first documented it, the syndrome is characterized by degeneration of kidney function and accumulation of fluids and wastes, leading to end-stage kidney disease at an early age. The condition generally affects males more severely than females. Children with Alport syndrome may initially experience leakage of small amounts of blood or protein into the urine. Although no specific treatment exists, Alport syndrome is best managed by controlling high blood pressure and using kidney protective medications called ACE (angiotensin converting enzyme) inhibitors and ARBs (angiotensin receptor blockers).
