What is adult acute myeloid leukemia?
Adult acute myeloid leukemia (AML) is a disease in which cancer (malignant) cells are found in the blood and bone marrow. AML is also called acute nonlymphocytic leukemia or ANLL. The bone marrow is the spongy tissue inside the large bones in the body. The bone marrow makes red blood cells (which carry oxygen and other materials to all tissues of the body), white blood cells (which fight infection), and platelets (which make the blood clot). Normally, the bone marrow makes cells called blasts that develop (mature) into several different types of blood cells that have specific jobs to do in the body. AML affects the blasts that are developing into white blood cells called granulocytes. In AML, the blasts do not mature and become too numerous. These immature blast cells are then found in the blood and the bone marrow. Leukemia can be acute (progressing quickly with many immature blasts) or chronic (progressing slowly with more mature looking cancer cells). Acute myeloid leukemia progress