What is acetaminophen, diphenhydramine, and phenylephrine?
Acetaminophen is a pain reliever and fever reducer. Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). The combination of acetaminophen, diphenhydramine, and phenylephrine is used to treat runny or stuffy nose, sinus congestion, sneezing, itchy nose, itchy or watery eyes, sore throat, cough, headache, and pain or fever caused by allergies or the common cold. This medication will not treat a cough that is caused by smoking, asthma, or emphysema. Acetaminophen, diphenhydramine, and phenylephrine may also be used for other purposes not listed in this medication guide.
