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What is a transcription factor (TF)?

April 26, 2017Factor TF transcription

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What is a transcription factor (TF)?

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A TF is a protein that binds to specific elements of DNA (recognition sites) to regulate the following expression of target genes. It can increase (as an activator) or decrease (as a repressor) the DNA binding of RNA polymerase, the enzyme that performs the transcription of genetic information from DNA to RNA. The resulting gene products (proteins) are afterwards important manager of the metabolism/ fate of a cell.