What is a reasonable (acceptable) proportion of buccal/saliva vs. blood samples in the full sample?
Blood samples are preferred on all subjects. However if a subject refuses to give blood, but would consent to saliva, then this is acceptable. Provisions would need to be made for accessing the DNA from buccal/saliva since it will not be processed or stored in the NIDA Repository. Additionally, the amount of DNA available to other investigators will need to be specified and pass peer review. There is no fixed proportion, but an estimate on the percentage of buccal/saliva samples with regard to the total sample would be helpful for review.
