What is a Malignant Hyperthermia (MH) crisis?
A MH-crisis can occur when a susceptible patient is exposed to triggering anesthesia agents. This exposure can lead to deranged muscle function, producing muscle rigidity, very high fever, deranged function or failure of other organs (kidney, lung), abnormal blood clotting and other life threatening complications. If treatment with dantrolene and other measures is not started promptly, up to 7 out of 10 patients may die from a MH-crisis and its complications.