What is a descripion of ribosomes?
Ribosomes are the machinery that translates the mRNA transcript to form a polypeptide chain that will fold into a protein. Ribosomes are formed of two subunits: 40S and 60S in eukaryotes, 30S and 70S in prokaryotes. Both subunits are comprised of ribosomal RNA (rRNA) and proteins. In eukaryotes, mRNA is recruited to the 40S subunit via the eIF4F mRNA cap-binding complex. Amino acids are recruited to the ribosome via eIF2, which binds to the initiatior-methione tRNA (met-tRNAi) which base pairs with the AUG start codon on the mRNA. the 60S subunit then joins and elongation can then start, with further amino acids being recruited to the now growing polypeptide chain by the other types of tRNA.