What information must be included in an animal use protocol reviewed by the IACUC?
Essential information includes an explanation of the reasons for and benefits of the use of animals, and an overview of the animal use, both written in layperson’s terms; proof that the work does not duplicate previous research and that no alternative to the use of live animals is available; description of all species, strains or types of animals to be used, the sources of the animals, the numbers needed, and justifications for the species and numbers; description of any specialized housing or care for the animals needed during the studies; detailed technical description of how the animals will be used, including any medications or materials administered to them; anesthetics and analgesics that will be administered to the animals; explanations if analgesics cannot be used (for a procedure during or after which the animals would normally be given analgesics) because of interference with the data collected during the study; a clear description of the endpoints of the studies; description
