What important data did the committee review when considering if the recommended immunization schedule can overload an infants immune system?
Central to concerns about multiple immunizations is whether the recommended immunization schedule overloads an infants immune system. This concern seems to be increasing as the number of recommended vaccines increases. However, the committee reviewed data that indicate that the number of antigens contained in the vaccines that make up the recommended childhood immunization schedule actually has decreased over the past 20 to 30 years, despite the increase in the number of vaccines and vaccine doses. This is due to removal of smallpox and whole cell pertussis vaccines from the childhood immunization schedule. The committee also reviewed estimates that suggest the capacity of the infant immune system is at least 1000 times greater than what is required to respond to immunization.
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